3-異丁基-1-甲基黃嘌呤
| 型 號： | I5879 |
| 報 價： |  |
3-異丁基-1-甲基黃嘌呤CAS號: 28822-58-4，貨號：I5879 ≥99% （HPLC）, powder
- 產(chǎn)品描述
品名：3-異丁基-1-甲基黃嘌呤
貨號：I5879
別名: 1-甲基-3-異丁基黃嘌呤, 3,7-二氫-1-甲基-3-（2-甲基丙基）-1H-嘌呤-2,6-二酮, 3-異丁基-1-甲基-2,6（1H,3H）-嘌呤二酮, IBMX
CAS號: 28822-58-4
經(jīng)驗分子式（希爾表示法）: C10H14N4O2
分子量: 222.24
Beilstein Registry Number: 247859
酶學委員會編號: 249-259-3
產(chǎn)品描述：
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包裝
1, 5 g in poly btl
100 mg in poly btl
250 mg in poly tube
Biochem/physiol Actions
Non-specific inhibitor of cAMP and cGMP phosphodiesterases. The increase in cAMP level as a result of phosphodiesterase inhibition by IBMX activates PKA leading to decreased proliferation, increased differentiation, and induction of apoptosis. IBMX inhibits phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa （IC50: 1.3 μM）. Also serves as an adenosine receptor antagonist. Shown to inhibit ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells. Induces calcium release from intracellular stores in sensory neurons.1
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